产品货号:
Z35554
中文名称:
Plexin A1/PLXNA1抗体
英文名称:
Anti-Plexin A1/PLXNA1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Plexin A1/PLXNA1 Antibody |
指标别名 | plexin A1;NOV;NOVP;PLEXIN-A1;PLXN1;PLXNA1 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | PLXNA1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human Plexin A1 Plays a role in axon guidance,invasive growth and cell migration. |
实际分子量 | 211KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Class 3 secreted semaphorin (Sema3A) is a chemorepellent that acts upon a wide variety of axons.As such,it induces a dramatic redistribution and depolymerization of actin filaments that results in growth cone collapse.Plexins are single membrane-spanning signaling proteins encompassing Plexin A1,A2,A3,and A4.Plexins form a complex with neuropilin-1 and -2 and the cell adhesion protein L1 to form a functional semaphorin receptor (1,2).The GTPase Rnd1 binds to the cytoplasmic domain of Plexin A1 to trigger cytoskeletal collapse.In contrast,the GTPase RhoD blocks Rnd1-mediated Plexin A1 activation and repulsion of sympathetic axons by Sema3A (3). |
Uniprot ID | Q9UIW2 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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